Disease: Optic Atrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
WARS2 Q9UGM6 tryptophanyl tRNA synthetase 2, mitochondrial 5.1E-02 0.617 0.577
TXNRD1 Q16881 thioredoxin reductase 1 Enzyme 1.6E-06 0.529 0.692
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
TSFM P43897 Ts translation elongation factor, mitochondrial Nucleic acid binding 1.9E-09 0.736 0.423
TRNW tRNA 0.563 0.731
TRNL1 tRNA 0.534 0.731
TRNK tRNA 0.608 0.577
TRNF tRNA 0.582 0.731
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TK2 O00142 thymidine kinase 2 Kinase 3.9E-07 0.585 0.615
TACO1 Q9BSH4 translational activator of cytochrome c oxidase I 1.5E-03 0.647 0.577
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
SLC25A46 Q96AG3 solute carrier family 25 member 46 Transporter 1.3E-05 0.695 0.308
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SERAC1 Q96JX3 serine active site containing 1 3.9E-06 0.686 0.385
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
SDHAF1 A6NFY7 succinate dehydrogenase complex assembly factor 1 8.7E-02 0.656 0.462
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846
SCO1 O75880 synthesis of cytochrome C oxidase 1 Enzyme 2.2E-04 0.638 0.769
SARDH Q9UL12 sarcosine dehydrogenase Enzyme 5.3E-16 0.523 0.846
PRPF6 O94906 pre-mRNA processing factor 6 Nucleic acid binding 3.2E-03 0.621 0.538
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846